Moisturizing creams are one of the most commonly used preparations in cosmetics with
numerous advantages, from effectiveness in the fight against dry skin to powerful mechanisms of
increasing the water content in the Stratum corneum of the skin (Figure 1), which achieves not
only the effect of skin hydration, but also the maintenance of normal pH of the skin. Dr Asya
Grafy offers a popular dermatological moisturizing cream product, which, in addition to its
proven effectiveness in hydration, also plays a role in the prevention and treatment of various
dermatological conditions. Drawing inspiration from the timeless therapeutic benefits of thermal
water and combining it with the latest scientific discoveries on botanical extracts,
THERMAOX® Antioxidant Moisturizer has been expertly formulated to deliver ultimate
hydration, nourishment, and rejuvenation to your skin, resulting in a more youthful and refreshed
look.

The application of this preparation increases the water content in the Stratum corneum of
the skin, which exerts a moisturizing effect and allows the lipid bilayers of the skin to normalize and regenerate, thus establishing their capacity to connect the corneocytes together and allow
moisture to be retained in the intercellular spaces (Figure 2).

INTERESTING HISTORY AND IDEA BEHIND ​​HYDRATING CREAMS
The first evidence of cosmetics and moisturizers dates back to Ancient Egypt around
6000 years ago. Surprisingly, there is no consensus on what a moisturizer is, despite having a
deep history. The word is a neologism invented by Madison Avenue advertisers to promote the
simplistic idea that it moisturizes the skin. The tendency to add oily materials to the skin is
almost instinctive and it can date back to the dawn of time. Moisturizers were once thought to
prevent transepidermal water loss (TEWL) by occlusion, preventing dryness, in addition to
maintaining skin smoothness and elasticity. The brick and mortar model suggests that the
Stratum corneum, although a dead layer, functions as an active membrane. Corneocytes are
bricks, with their tough cell membranes and keratin microfibrils, while the lipid layers between
the cells are mortar (Figure 3). The loss of dominant intercellular lipids that play a vital role in
skin humidity by forming a bilayer, such as ceramides, cholesterol and fatty acids, leads to
damage to the water barrier structure, resulting in dry skin. When the moisture content of the
skin falls below 10% and the Stratum corneum loses its continuity, it is considered dry.

THE BENEFITS OF ANTIOXIDANT ENRICHED MOISTURIZERS

REVEAL THE SECRET TO YOUTHFUL SKIN!
Motivated by the ancient wisdom surrounding the healing powers of thermal water and
the latest scientific discoveries in botanical extracts, the THERMAOX Antioxidant Enriched
Moisturizer represents the pinnacle of innovation in skincare. This extraordinary moisturizer
harnesses the benefits of the THERMAOX complex, which consists of a powerful blend of
Slovenian thermal water, renowned for its rich mineral content, combined with essential vitamins
E, C, B5, B3, B6, and CoQ10. Additionally, it includes rosmarinic antioxidants and the hydrating
properties of hyaluronic acid, squalane, and pomegranate oil. This advanced formulation is
further enriched with the remarkable effects of blueberry and moss extracts, as well as the natural
retinol, like bakuchiol, providing deep benefits for your skin:
 Hydrate
 Balance
 Nourish
 Regenerate

The application of moisturizers, such as this THERMAOX product, has demonstrated
support for various biological functions. They play a crucial role in maintaining skin hydration,
reducing friction, and improving mechanical properties. A single application can provoke
immediate changes, such as increased skin softness and reduced temperature, while repeated use
leads to improved hydration and overall skin texture. Additionally, they can reduce the need for
corticosteroids by maintaining skin moisture and integrity. The effectiveness of moisturizers can
vary depending on skin type, from oil-free formulations for oily skin to richer compositions for
dry skin, but their fundamental roles include enhancing skin softness and hydration, improving
appearance, and supporting the skin barrier function. The THERMAOX Antioxidant Enriched
Moisturizer not only hydrates and nourishes the skin but also protects and rejuvenates it, offering
a comprehensive solution for achieving and maintaining healthy, radiant skin.

WHAT’S INSIDE THE MAGIC OF OUR CREAM?
THERMAOX® Antioxidant Enriched Moisturizer (Figure 4) is a hydrating cream
enriched with a carefully selected blend of natural ingredients that synergistically nourish,
protect, and rejuvenate your skin.

Each component is highly potent, offers remarkable benefits, and constitutes an important
part of this complex and effective hydrating cream:

1. Natural oils and butter: These are rich in fatty acids, including oleic and linoleic acids,
   which help hydrate and nourish the skin. Enriched with vitamins A, B1, B2, D, and E,
   they also provide natural UV-A and UV-B protection, shielding your skin from harmful
   sun rays while promoting regeneration and softness.
2. Soluble collagen: Plays a vital role in maintaining skin hydration and elasticity by
   forming a protective barrier. It helps rejuvenate the skin’s texture, making it smoother and
   more resilient.
3. Rosmarinic extract: Known for its powerful antioxidant, antimicrobial, and anti-
   inflammatory properties, rosmarinic extract provides a strong rejuvenating effect on the
   skin. It helps combat oxidative stress, making it a valuable ally in maintaining skin
   health.
4. Aloe Vera: Renowned for its moisturizing and soothing properties, Aloe Vera effectively
   hydrates and softens the skin, alleviates irritation, and reduces fine lines and wrinkles,
   promoting a youthful complexion.
5. Vaccinium Myrtillus (blueberry) extract: Offers antioxidant effects and inhibits
   hyperpigmentation. It helps maintain levels of hyaluronic acid in the skin and improves
   the skin’s protective barrier, enhancing overall skin health.
6. Moss extract: Rich in protective properties, moss extract shields skin cells from external
   stressors while rejuvenating them. It increases hydration, reduces water loss, and
   improves the skin’s barrier function, ensuring your skin remains soft and resilient.
7. Bakuchiol: A natural alternative to retinol, bakuchiol is known for its gentler profile and
   better tolerance. It stimulates collagen synthesis, reduces hyperpigmentation, diminishes
   the appearance of wrinkles, and enhances the skin’s defense against stress.
8. Hyaluronic acid: A top-tier skincare ingredient crucial for maintaining skin hydration.
   Its low molecular weight allows it to penetrate deeply, providing intense hydration and
   restoring softness to the skin. It also promotes cell regeneration, reducing fine lines and
   improving overall texture.
9. Vitamins:

 Vitamin E: Protects against cell damage and supports wound healing.
 Vitamin B6: Helps regulate sebum production, reducing oily spots.
 Vitamin B5: Promotes cell regeneration and has anti-inflammatory properties.
 Vitamin B3: Enhances barrier function, improves skin texture and tone,
reduces fine lines and environmental damage.
 Vitamin C: A powerful antioxidant that stimulates collagen synthesis,
improves skin elasticity, and fights hyperpigmentation and wrinkles.

10. Slovenian thermal water: Enriched with minerals that enhance skin function, hydration,
    and detoxification, acting as an electrolyte, antioxidant, and anti-inflammatory agent,
    nourishing the skin.
    GIVE YOUR SKIN THE CARE IT DESERVES, AND WATCH IT

RADIATE LIKE THE SUN!
Every ingredient in our moisturizer has been meticulously selected, not just for its
individual benefits, but also for its synergistic ability to work in harmony with one another. This
thoughtful formulation creates a powerful blend that transforms and protects your skin, ensuring
that it receives the nourishment it truly deserves. By treating your skin with this exquisite
combination of natural treasures, you can unlock its inherent radiance, allowing it to flourish and
glow like never before. Embrace this luxurious skincare experience and witness the remarkable
results as your complexion becomes revitalized, vibrant, and luminous. Your skin is a reflection
of your inner beauty, so indulge it with the care it needs to shine brightly, and revel in the
confidence that comes from healthy, glowing skin.

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